Why the model matters
Almost every other price in American pharmacy is the output of a negotiation you are not party to. Cost Plus inverts that: it publishes what it paid, what it adds, and what it charges to dispense and ship. You can check the arithmetic.
For ED specifically, that matters because the category is saturated with subscriptions whose per-dose pricing is designed to be hard to compare. A published formula is the cleanest available benchmark for judging whether any other offer is reasonable.
Where it does not fit
- You need a prescription first. This solves cost, not access.
- Delivery takes days. If you want something for the weekend, this is not the route.
- Formulary limits apply. Availability of specific medications and strengths changes; verify rather than assume.
- Brand-name products are not where this model shines.
- Very small orders are diluted by the fixed pharmacy and shipping fees — larger quantities make the arithmetic work better.
Reviewed individually
Cost Plus Drugs sells several different things, and they are not equivalent — some are FDA-approved generics, some are brand-name originals, and some are compounded formulations that have not been through FDA review. Each is reviewed separately, with the retail price of the same molecule shown alongside.
- Generic4.6
Generic sildenafil
Sildenafil citrate
The same FDA-approved generic as everywhere else, sold with the markup published. It is the clearest price benchmark available in this whole category.
Read the review → - Generic4.7
Generic tadalafil
Tadalafil
Generic tadalafil at a published markup. Because tadalafil needs fewer doses than sildenafil for the same coverage, this is frequently the lowest annual cost available anywhere.
Read the review →
Frequently asked questions
Does Cost Plus Drugs carry ED medication?
Do I need a prescription?
Is it cheaper than GoodRx?
Why is it so much cheaper than brand pricing?
What this is based on
We link to primary sources — clinical guidelines, regulator publications and peer-reviewed research — wherever possible. Links open on third-party sites we do not control.
- [01]National Association of Boards of Pharmacy. Digital Pharmacy Accreditation and safe site listings.
- [02]U.S. Food and Drug Administration. BeSafeRx: Your Source for Online Pharmacy Information.
- [03]U.S. Food and Drug Administration. Counterfeit Medicine.